Disorders of immune dysregulation
Gene: LYST

LYST (lysosomal trafficking regulator)
EnsemblGeneIds (GRCh38): ENSG00000143669
EnsemblGeneIds (GRCh37): ENSG00000143669
OMIM: 606897, Gene2Phenotype
LYST is in 18 panels

1 review

Krithika Murali (Victorian Clinical Genetics Services)

Green List (high evidence)

Well-established gene disease association
Created: 20 May 2022, 12:35 a.m. | Last Modified: 20 May 2022, 12:35 a.m.

Panel Version: 0.14660

Mode of inheritance
BIALLELIC, autosomal or pseudoautosomal

Phenotypes
Chediak-Higashi syndrome - MIM#214500

Created: 20 May 2022, 12:35 a.m.
Last Modified: 20 May 2022, 12:35 a.m.
Panel version: Imported from Mendeliome panel version 0.14660

Details

Mode of Inheritance

Unknown

Sources

Melbourne Genomics Health Alliance Immunology Flagship
Victorian Clinical Genetics Services
Expert Review Green

Tags

treatable

OMIM

606897

Clinvar variants

Variants in LYST

Penetrance

None

Panels with this gene

History Filter Activity

27 Sep 2022, Gel status: 3

Added Tag

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

Tag treatable tag was added to gene: LYST.

17 Nov 2019, Gel status: 3

Created, Added New Source, Set mode of inheritance

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

gene: LYST was added gene: LYST was added to Disorders of immune dysregulation_MGHA_AGHA_VCGS. Sources: Expert Review Green,Victorian Clinical Genetics Services,Melbourne Genomics Health Alliance Immunology Flagship Mode of inheritance for gene: LYST was set to Unknown

Disorders of immune dysregulation Gene: LYST