Disorders of immune dysregulation
Gene: IL10RB

IL10RB (interleukin 10 receptor subunit beta)
EnsemblGeneIds (GRCh38): ENSG00000243646
EnsemblGeneIds (GRCh37): ENSG00000243646
OMIM: 123889, Gene2Phenotype
IL10RB is in 9 panels

1 review

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

Green List (high evidence)

Multiple families reported.
Created: 17 Mar 2022, 8:54 p.m. | Last Modified: 17 Mar 2022, 8:54 p.m.

Panel Version: 0.11526

Mode of inheritance
BIALLELIC, autosomal or pseudoautosomal

Phenotypes
Inflammatory bowel disease 25, early onset, autosomal recessive, MIM# 612567

Publications

Created: 17 Mar 2022, 8:54 p.m.
Last Modified: 17 Mar 2022, 8:54 p.m.
Panel version: Imported from Mendeliome panel version 0.11526

Details

Mode of Inheritance

Unknown

Sources

Expert Review Green
Melbourne Genomics Health Alliance Immunology Flagship
Victorian Clinical Genetics Services
Expert Review Green
Victorian Clinical Genetics Services

OMIM

123889

Clinvar variants

Variants in IL10RB

Penetrance

None

Panels with this gene

History Filter Activity

17 Nov 2019, Gel status: 3

Created, Added New Source, Set mode of inheritance

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

gene: IL10RB was added gene: IL10RB was added to Disorders of immune dysregulation_MGHA_AGHA_VCGS. Sources: Expert Review Green,Victorian Clinical Genetics Services,Melbourne Genomics Health Alliance Immunology Flagship Mode of inheritance for gene: IL10RB was set to Unknown

Disorders of immune dysregulation Gene: IL10RB