Disorders of immune dysregulation
Gene: FGL2
Homozygous truncating variant, functional studies include rescue experiments.Created: 28 Oct 2022, 7:10 a.m. | Last Modified: 28 Oct 2022, 7:10 a.m.
Panel Version: 0.160
Mode of inheritance
BIALLELIC, autosomal or pseudoautosomal
Phenotypes
Autoinflammatory syndrome, MONDO:0019751, FGL2-related
Child with early onset systemic inflammation, autoantibodies, and vasculitis with supportive functional data
Sources: LiteratureCreated: 28 Oct 2022, 4:45 a.m.
Mode of inheritance
BIALLELIC, autosomal or pseudoautosomal
Phenotypes
Immune dysregulation
Publications
Gene: fgl2 has been classified as Amber List (Moderate Evidence).
Phenotypes for gene: FGL2 were changed from Immune dysregulation to Autoinflammatory syndrome, MONDO:0019751, FGL2-related
Gene: fgl2 has been classified as Amber List (Moderate Evidence).
gene: FGL2 was added gene: FGL2 was added to Disorders of immune dysregulation. Sources: Literature Mode of inheritance for gene: FGL2 was set to BIALLELIC, autosomal or pseudoautosomal Publications for gene: FGL2 were set to PMID: 36243222 Phenotypes for gene: FGL2 were set to Immune dysregulation Review for gene: FGL2 was set to RED