Combined Immunodeficiency
Gene: MOGSEnsemblGeneIds (GRCh38): ENSG00000115275
EnsemblGeneIds (GRCh37): ENSG00000115275
OMIM: 601336, Gene2Phenotype
MOGS is in 13 panels
1 review
Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)
Three families reported.
Sources: Expert listCreated: 3 Apr 2020, 8:52 a.m.
Mode of inheritance
BIALLELIC, autosomal or pseudoautosomal
Phenotypes
Congenital disorder of glycosylation, type IIb, MIM# 606056; Severe hypogammaglobulinaemia; Bacterial and viral infections; Severe neurologic disease
Publications
Details
- Mode of Inheritance
- BIALLELIC, autosomal or pseudoautosomal
- Sources
-
- Expert Review Green
- Expert list
- Phenotypes
-
- Congenital disorder of glycosylation, type IIb, MIM# 606056
- Severe hypogammaglobulinaemia
- Bacterial and viral infections
- Severe neurologic disease
- OMIM
- 601336
- Clinvar variants
- Variants in MOGS
- Penetrance
- None
- Publications
- Panels with this gene
-
- Common Variable Immunodeficiency
- Predominantly Antibody Deficiency
- Mackenzie's Mission_Reproductive Carrier Screening
- Combined Immunodeficiency
- Congenital Disorders of Glycosylation
- Fetal anomalies
- Additional findings_Paediatric
- Prepair 1000+
- Dystonia - complex
- Mendeliome
- BabyScreen+ newborn screening
- Intellectual disability syndromic and non-syndromic
- Genetic Epilepsy
History Filter Activity
Entity classified by Genomics England curator
Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)Gene: mogs has been classified as Green List (High Evidence).
Entity classified by Genomics England curator
Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)Gene: mogs has been classified as Green List (High Evidence).
Created, Added New Source, Set mode of inheritance, Set publications, Set Phenotypes
Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)gene: MOGS was added gene: MOGS was added to Combined Immunodeficiency. Sources: Expert list Mode of inheritance for gene: MOGS was set to BIALLELIC, autosomal or pseudoautosomal Publications for gene: MOGS were set to 10788335; 24716661; 29235540 Phenotypes for gene: MOGS were set to Congenital disorder of glycosylation, type IIb, MIM# 606056; Severe hypogammaglobulinaemia; Bacterial and viral infections; Severe neurologic disease Review for gene: MOGS was set to GREEN