1. Panels
  2. Combined Immunodeficiency
  3. ICOSLG
STRs in panel
Prev Next
Regions in panel
Prev Next

Combined Immunodeficiency

Gene: ICOSLG

Amber List (moderate evidence)
ICOSLG (inducible T-cell costimulator ligand)
EnsemblGeneIds (GRCh38): ENSG00000160223
EnsemblGeneIds (GRCh37): ENSG00000160223
OMIM: 605717, Gene2Phenotype
ICOSLG is in 3 panels

1 review

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

I don't know

One, possibly two, reports (one not in English), some functional data.
Sources: Expert list
Created: 3 Apr 2020, 3:11 a.m.

Mode of inheritance
BIALLELIC, autosomal or pseudoautosomal

Phenotypes
Immunodeficiency 119, MIM# 620825; Combined immunodeficiency; recurrent bacterial and viral infections; neutropaenia

Publications

Created: 3 Apr 2020, 3:11 a.m.

Panel version: 1.63

Details

Mode of Inheritance
BIALLELIC, autosomal or pseudoautosomal
Sources
  • Expert Review Amber
  • Expert list
Phenotypes
  • Immunodeficiency 119, MIM# 620825
  • Combined immunodeficiency
  • recurrent bacterial and viral infections
  • neutropaenia
OMIM
605717
Clinvar variants
Variants in ICOSLG
Penetrance
None
Publications
Panels with this gene

History Filter Activity

2 Jun 2024, Gel status: 2

Set Phenotypes

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

Phenotypes for gene: ICOSLG were changed from Combined immunodeficiency; recurrent bacterial and viral infections; neutropaenia to Immunodeficiency 119, MIM# 620825; Combined immunodeficiency; recurrent bacterial and viral infections; neutropaenia

3 Apr 2020, Gel status: 2

Entity classified by Genomics England curator

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

Gene: icoslg has been classified as Amber List (Moderate Evidence).

3 Apr 2020, Gel status: 2

Entity classified by Genomics England curator

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

Gene: icoslg has been classified as Amber List (Moderate Evidence).

3 Apr 2020, Gel status: 1

Created, Added New Source, Set mode of inheritance, Set publications, Set Phenotypes

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

gene: ICOSLG was added gene: ICOSLG was added to Combined Immunodeficiency. Sources: Expert list Mode of inheritance for gene: ICOSLG was set to BIALLELIC, autosomal or pseudoautosomal Publications for gene: ICOSLG were set to 31532372; 30498080 Phenotypes for gene: ICOSLG were set to Combined immunodeficiency; recurrent bacterial and viral infections; neutropaenia Review for gene: ICOSLG was set to AMBER