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  3. ZIC4
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Regression

Gene: ZIC4

Red List (low evidence)
ZIC4 (Zic family member 4)
EnsemblGeneIds (GRCh38): ENSG00000174963
EnsemblGeneIds (GRCh37): ENSG00000174963
OMIM: 608948, Gene2Phenotype
ZIC4 is in 3 panels

3 reviews

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

Comment when marking as ready: Two individuals with deletions of ZIC4 and ZIC1 reported with Dandy-Walker malformation.
Created: 20 Jan 2022, 11:40 p.m. | Last Modified: 20 Jan 2022, 11:40 p.m.
Panel Version: 0.393
Created: 20 Jan 2022, 11:40 p.m.
Last Modified: 20 Jan 2022, 11:40 p.m.
Panel version: 0.393

Michelle Torres (Victorian Clinical Genetics Services)

Red List (low evidence)

No evidence supporting gene/disease association.
No OMIM phenotype. Gene is not in PanelApp UK. No P/LP SNV reported in ClinVar
Created: 18 Jan 2022, 12:20 a.m. | Last Modified: 18 Jan 2022, 12:20 a.m.
Panel Version: 0.391

Mode of inheritance
Unknown

Publications

Created: 18 Jan 2022, 12:20 a.m.
Last Modified: 18 Jan 2022, 12:20 a.m.
Panel version: 0.391

Crystle Lee (Victorian Clinical Genetics Services)

Red List (low evidence)

No evidence supporting gene/disease association.
No OMIM phenotype. Gene is not in PanelApp UK. No P/LP SNV reported in ClinVar
Created: 4 May 2020, 3:03 a.m. | Last Modified: 4 May 2020, 3:03 a.m.
Panel Version: 0.116

Mode of inheritance
Unknown

Publications

Created: 4 May 2020, 3:03 a.m.
Last Modified: 4 May 2020, 3:03 a.m.
Panel version: 0.116

Details

Mode of Inheritance
Unknown
Sources
  • Expert Review Red
  • Victorian Clinical Genetics Services
OMIM
608948
Clinvar variants
Variants in ZIC4
Penetrance
None
Publications
Panels with this gene

History Filter Activity

20 Jan 2022, Gel status: 1

Entity classified by Genomics England curator

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

Gene: zic4 has been classified as Red List (Low Evidence).

20 Jan 2022, Gel status: 1

Set publications

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

Publications for gene: ZIC4 were set to

20 Jan 2022, Gel status: 1

Entity classified by Genomics England curator

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

Gene: zic4 has been classified as Red List (Low Evidence).

17 Nov 2019, Gel status: 3

Created, Added New Source, Set mode of inheritance

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

gene: ZIC4 was added gene: ZIC4 was added to Regression_VCGS. Sources: Expert Review Green,Victorian Clinical Genetics Services Mode of inheritance for gene: ZIC4 was set to Unknown