Callosome
Gene: LHX3
Comment when marking as ready: Gene not associated with absence of corpus callosum.Created: 28 Mar 2022, 2:24 a.m. | Last Modified: 28 Mar 2022, 2:24 a.m.
Panel Version: 0.428
Causes anterior pituitary hypoplasia and hormone deficiency, deafness, short neck with restricted movements. Absence of corpus callosum not a typical feature.Created: 28 Mar 2022, 2:21 a.m. | Last Modified: 28 Mar 2022, 2:21 a.m.
Panel Version: 0.425
Mode of inheritance
BIALLELIC, autosomal or pseudoautosomal
Phenotypes
Pituitary hormone deficiency, combined, 3, MIM# 221750
Variants in this GENE are reported as part of current diagnostic practice
Gene: lhx3 has been classified as Red List (Low Evidence).
Phenotypes for gene: LHX3 were changed from Pituitary hormone deficiency, combined, 3, MIM# 221750 to Pituitary hormone deficiency, combined, 3, MIM# 221750
Mode of inheritance for gene: LHX3 was changed from BIALLELIC, autosomal or pseudoautosomal to BIALLELIC, autosomal or pseudoautosomal
Phenotypes for gene: LHX3 were changed from to Pituitary hormone deficiency, combined, 3, MIM# 221750
Mode of inheritance for gene: LHX3 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal
Gene: lhx3 has been classified as Red List (Low Evidence).
gene: LHX3 was added gene: LHX3 was added to Corpus callosum agenesis, Callosome_VCGS. Sources: Expert Review Green,Victorian Clinical Genetics Services Mode of inheritance for gene: LHX3 was set to Unknown