This panel was developed and is maintained by VCGS.
Sick sinus syndrome encompasses a variety of conditions caused by sinus node dysfunction. The most common clinical manifestations are syncope, presyncope, dizziness, and fatigue. Electrocardiogram typically shows sinus bradycardia, sinus arrest, and/or sinoatrial block. Episodes of atrial tachycardias coexisting with sinus bradycardia ('tachycardia-bradycardia syndrome') are also common in this disorder.
Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)
Chirag Patel (Genetic Health Queensland)
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4 Entitiess
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HCN4 |
1 review1 green |
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted |
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POPDC2 |
1 review1 green |
BIALLELIC, autosomal or pseudoautosomal |
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SCN5A |
1 review1 green |
BIALLELIC, autosomal or pseudoautosomal |
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GNB2 |
1 review1 red |
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted |
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Phenotypes
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2021-08-01 06:00 Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics) promoted panel to 1.0
Fully reviewed and promoted to V1.