Rasopathy
Gene: NRAS
Over 20 affected individuals reported, well established gene-disease association.Created: 11 Sep 2020, 10:46 a.m. | Last Modified: 11 Sep 2020, 10:46 a.m.
Panel Version: 0.59
Mode of inheritance
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Phenotypes
Noonan syndrome 6, MIM# 613224
Publications
Mode of pathogenicity
Loss-of-function variants (as defined in pop up message) DO NOT cause this phenotype - please provide details in the comments
Gene: nras has been classified as Green List (High Evidence).
Phenotypes for gene: NRAS were changed from to Noonan syndrome 6, MIM# 613224
Publications for gene: NRAS were set to
Mode of pathogenicity for gene: NRAS was changed from to Loss-of-function variants (as defined in pop up message) DO NOT cause this phenotype - please provide details in the comments
Mode of inheritance for gene: NRAS was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
gene: NRAS was added gene: NRAS was added to Rasopathy_VCGS. Sources: Expert Review Green,Victorian Clinical Genetics Services Mode of inheritance for gene: NRAS was set to Unknown