Polydactyly
Gene: ZNF141

ZNF141 (zinc finger protein 141)
EnsemblGeneIds (GRCh38): ENSG00000131127
EnsemblGeneIds (GRCh37): ENSG00000131127
OMIM: 194648, Gene2Phenotype
ZNF141 is in 2 panels

2 reviews

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

Red List (low evidence)

Single consanguineous family reported in 2013, where a homozygous missense variant segregated with polydactyly in four affected individuals. No supporting evidence and no further reports identified.
Created: 21 Jul 2020, 9:14 p.m. | Last Modified: 21 Jul 2020, 9:14 p.m.

Panel Version: 0.158

Mode of inheritance
BIALLELIC, autosomal or pseudoautosomal

Phenotypes
Polydactyly, postaxial, type A6, MIM# 615226

Publications

23160277

Created: 21 Jul 2020, 9:14 p.m.
Last Modified: 21 Jul 2020, 9:14 p.m.
Panel version: 0.158

Anand Vasudevan (Royal Women's Hospital)

Mode of inheritance
BIALLELIC, autosomal or pseudoautosomal

Created: 21 Jul 2020, 4:24 a.m.
Last Modified: 21 Jul 2020, 4:24 a.m.
Panel version: 0.36

Details

Mode of Inheritance

BIALLELIC, autosomal or pseudoautosomal

Sources

Expert Review Red
Victorian Clinical Genetics Services

Phenotypes

Polydactyly, postaxial, type A6, MIM# 615226

OMIM

194648

Clinvar variants

Variants in ZNF141

Penetrance

None

Publications

23160277

Panels with this gene