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  2. Cancer Predisposition_Paediatric
  3. REST
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Cancer Predisposition_Paediatric

Gene: REST

Green List (high evidence)
REST (RE1 silencing transcription factor)
EnsemblGeneIds (GRCh38): ENSG00000084093
EnsemblGeneIds (GRCh37): ENSG00000084093
OMIM: 600571, Gene2Phenotype
REST is in 5 panels

1 review

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

Green List (high evidence)

More than 10 families reported.
Sources: Expert Review
Created: 25 Jul 2022, 1:40 a.m.

Mode of inheritance
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted

Phenotypes
{Wilms tumor 6, susceptibility to}, MIM# 616806

Publications

Created: 25 Jul 2022, 1:40 a.m.

Panel version: 0.121

Details

Mode of Inheritance
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Sources
  • Expert Review Green
  • Expert Review
Phenotypes
  • {Wilms tumor 6, susceptibility to}, MIM# 616806
OMIM
600571
Clinvar variants
Variants in REST
Penetrance
None
Publications
Panels with this gene

History Filter Activity

25 Jul 2022, Gel status: 3

Entity classified by Genomics England curator

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

Gene: rest has been classified as Green List (High Evidence).

25 Jul 2022, Gel status: 3

Entity classified by Genomics England curator

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

Gene: rest has been classified as Green List (High Evidence).

25 Jul 2022, Gel status: 1

Created, Added New Source, Set mode of inheritance, Set publications, Set Phenotypes

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

gene: REST was added gene: REST was added to Cancer Predisposition_Paediatric. Sources: Expert Review Mode of inheritance for gene: REST was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted Publications for gene: REST were set to 26551668; 34308104 Phenotypes for gene: REST were set to {Wilms tumor 6, susceptibility to}, MIM# 616806 Review for gene: REST was set to GREEN