1. Panels
  2. Cancer Predisposition_Paediatric
  3. HRAS
STRs in panel
Prev Next
Regions in panel
Prev Next

Cancer Predisposition_Paediatric

Gene: HRAS

Green List (high evidence)
HRAS (HRas proto-oncogene, GTPase)
EnsemblGeneIds (GRCh38): ENSG00000174775
EnsemblGeneIds (GRCh37): ENSG00000174775
OMIM: 190020, Gene2Phenotype
HRAS is in 22 panels

1 review

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

Green List (high evidence)

Increased risk of epithelioma, bladder carcinoma, rhabdomyosarcoma, vestibular schwannoma
Created: 1 Aug 2020, 7:58 a.m. | Last Modified: 1 Aug 2020, 7:58 a.m.
Panel Version: 0.51

Mode of inheritance
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted

Phenotypes
Costello syndrome, MIM# 218040

Created: 1 Aug 2020, 7:58 a.m.
Last Modified: 1 Aug 2020, 7:58 a.m.
Panel version: 0.51

History Filter Activity

1 Aug 2020, Gel status: 3

Entity classified by Genomics England curator

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

Gene: hras has been classified as Green List (High Evidence).

1 Aug 2020, Gel status: 3

Set Phenotypes

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

Phenotypes for gene: HRAS were changed from to Costello syndrome, MIM# 218040

1 Aug 2020, Gel status: 3

Set mode of inheritance

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

Mode of inheritance for gene: HRAS was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted

17 Nov 2019, Gel status: 3

Created, Added New Source, Set mode of inheritance

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

gene: HRAS was added gene: HRAS was added to Paediatric Cancer Predisposition_VCGS. Sources: Expert Review Green,Victorian Clinical Genetics Services Mode of inheritance for gene: HRAS was set to Unknown