Cancer Predisposition_Paediatric
Gene: CTR9EnsemblGeneIds (GRCh38): ENSG00000198730
EnsemblGeneIds (GRCh37): ENSG00000198730
OMIM: 609366, Gene2Phenotype
CTR9 is in 6 panels
1 review
Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)
Four unrelated families reported, where germline variants segregated with disease. Postulated to be a tumour suppressor gene.
Note variants in this gene have also been associated with a neurodevelopmental disorder.
Sources: Expert ReviewCreated: 22 Jul 2022, 8:26 a.m.
Mode of inheritance
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Phenotypes
Familial Wilms tumour, MONDO:0006058, CTR9-related
Publications
Details
- Mode of Inheritance
- MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
- Sources
-
- Expert Review Green
- Expert Review
- Phenotypes
-
- Familial Wilms tumour, MONDO:0006058, CTR9-related
- OMIM
- 609366
- Clinvar variants
- Variants in CTR9
- Penetrance
- None
- Publications
- Panels with this gene
History Filter Activity
Entity classified by Genomics England curator
Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)Gene: ctr9 has been classified as Green List (High Evidence).
Entity classified by Genomics England curator
Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)Gene: ctr9 has been classified as Green List (High Evidence).
Created, Added New Source, Set mode of inheritance, Set publications, Set Phenotypes
Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)gene: CTR9 was added gene: CTR9 was added to Cancer Predisposition_Paediatric. Sources: Expert Review Mode of inheritance for gene: CTR9 was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted Publications for gene: CTR9 were set to 25099282; 29292210 Phenotypes for gene: CTR9 were set to Familial Wilms tumour, MONDO:0006058, CTR9-related Review for gene: CTR9 was set to GREEN