1. Panels
  2. Proteinuria
  3. SPRY2
STRs in panel
Prev Next
Regions in panel
Prev Next

Proteinuria

Gene: SPRY2

Red List (low evidence)
SPRY2 (sprouty RTK signaling antagonist 2)
EnsemblGeneIds (GRCh38): ENSG00000136158
EnsemblGeneIds (GRCh37): ENSG00000136158
OMIM: 602466, Gene2Phenotype
SPRY2 is in 1 panel

1 review

Bryony Thompson (Royal Melbourne Hospital)

Red List (low evidence)

A single family reported with expression analyses conducted in some patient cells. No variants identified in 70 apparently sporadic cases with IgAN.
Sources: Literature
Created: 25 Jun 2021, 12:54 a.m. | Last Modified: 25 Jun 2021, 12:55 a.m.
Panel Version: 0.169

Mode of inheritance
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted

Phenotypes
{?IgA nephropathy, susceptibility to, 3} MIM#616818

Publications

Created: 25 Jun 2021, 12:54 a.m.
Last Modified: 25 Jun 2021, 12:55 a.m.
Panel version: 0.169

Details

Mode of Inheritance
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Sources
  • Expert Review Red
  • Literature
Phenotypes
  • {?IgA nephropathy, susceptibility to, 3} MIM#616818
OMIM
602466
Clinvar variants
Variants in SPRY2
Penetrance
None
Publications
Panels with this gene

History Filter Activity

25 Jun 2021, Gel status: 1

Entity classified by Genomics England curator

Bryony Thompson (Royal Melbourne Hospital)

Gene: spry2 has been classified as Red List (Low Evidence).

25 Jun 2021, Gel status: 1

Created, Added New Source, Set mode of inheritance, Set publications, Set Phenotypes

Bryony Thompson (Royal Melbourne Hospital)

gene: SPRY2 was added gene: SPRY2 was added to Proteinuria. Sources: Literature Mode of inheritance for gene: SPRY2 was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted Publications for gene: SPRY2 were set to 25782674 Phenotypes for gene: SPRY2 were set to {?IgA nephropathy, susceptibility to, 3} MIM#616818 Review for gene: SPRY2 was set to RED