1. Panels
  2. Proteinuria
  3. KANK4
STRs in panel
Prev Next
Regions in panel
Prev Next

Proteinuria

Gene: KANK4

Red List (low evidence)
KANK4 (KN motif and ankyrin repeat domains 4)
EnsemblGeneIds (GRCh38): ENSG00000132854
EnsemblGeneIds (GRCh37): ENSG00000132854
OMIM: 614612, Gene2Phenotype
KANK4 is in 2 panels

2 reviews

Chirag Patel (Genetic Health Queensland)

Red List (low evidence)

Discussed with Z Stark as part of review - downgraded.
Created: 9 Jan 2020, 3:42 a.m. | Last Modified: 9 Jan 2020, 3:42 a.m.
Panel Version: 0.78
Created: 9 Jan 2020, 3:42 a.m.
Last Modified: 9 Jan 2020, 3:42 a.m.
Panel version: 0.78

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

I don't know

Single family with two affected individuals reported; belongs to family of proteins implicated in nephrotic syndrome.
Sources: Expert list
Created: 20 Dec 2019, 2:34 a.m.

Mode of inheritance
BIALLELIC, autosomal or pseudoautosomal

Phenotypes
Nephrotic syndrome

Publications

Created: 20 Dec 2019, 2:34 a.m.

Panel version: 0.106

Details

Mode of Inheritance
BIALLELIC, autosomal or pseudoautosomal
Sources
  • Expert Review Red
  • Expert list
OMIM
614612
Clinvar variants
Variants in KANK4
Penetrance
None
Publications
Panels with this gene

History Filter Activity

9 Jan 2020, Gel status: 1

Entity classified by Genomics England curator

Chirag Patel (Genetic Health Queensland)

Gene: kank4 has been classified as Red List (Low Evidence).

20 Dec 2019, Gel status: 2

Entity classified by Genomics England curator

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

Gene: kank4 has been classified as Amber List (Moderate Evidence).

20 Dec 2019, Gel status: 2

Entity classified by Genomics England curator

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

Gene: kank4 has been classified as Amber List (Moderate Evidence).

20 Dec 2019, Gel status: 1

Created, Added New Source, Set mode of inheritance, Set publications

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

gene: KANK4 was added gene: KANK4 was added to Proteinuria_VCGS_KidGen. Sources: Expert list Mode of inheritance for gene: KANK4 was set to BIALLELIC, autosomal or pseudoautosomal Publications for gene: KANK4 were set to 25961457 Review for gene: KANK4 was set to AMBER