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Mendeliome

Gene: VTN

Red List (low evidence)

VTN (vitronectin)
EnsemblGeneIds (GRCh38): ENSG00000109072
EnsemblGeneIds (GRCh37): ENSG00000109072
OMIM: 193190, Gene2Phenotype
VTN is in 2 panels

1 review

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

Red List (low evidence)

Over-representation in cases vs controls but no functional data and mechanism unclear at present.
Created: 9 Jan 2020, 10:01 a.m. | Last Modified: 9 Jan 2020, 10:01 a.m.
Panel Version: 0.734

Mode of inheritance
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted

Phenotypes
Atypical haemolytic uraemic syndrome

Publications

Details

Mode of Inheritance
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Sources
  • Expert Review Red
  • Victorian Clinical Genetics Services
Phenotypes
  • Atypical haemolytic uraemic syndrome
OMIM
193190
Clinvar variants
Variants in VTN
Penetrance
None
Publications
Panels with this gene

History Filter Activity

9 Jan 2020, Gel status: 1

Entity classified by Genomics England curator

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

Gene: vtn has been classified as Red List (Low Evidence).

9 Jan 2020, Gel status: 1

Set Phenotypes

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

Phenotypes for gene: VTN were changed from to Atypical haemolytic uraemic syndrome

9 Jan 2020, Gel status: 1

Set publications

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

Publications for gene: VTN were set to

9 Jan 2020, Gel status: 1

Set mode of inheritance

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

Mode of inheritance for gene: VTN was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted

9 Jan 2020, Gel status: 1

Entity classified by Genomics England curator

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

Gene: vtn has been classified as Red List (Low Evidence).

17 Nov 2019, Gel status: 3

Created, Added New Source, Set mode of inheritance

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

gene: VTN was added gene: VTN was added to Mendeliome_VCGS. Sources: Expert Review Green,Victorian Clinical Genetics Services Mode of inheritance for gene: VTN was set to Unknown