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Mendeliome

Gene: NR0B2

Red List (low evidence)

NR0B2 (nuclear receptor subfamily 0 group B member 2)
EnsemblGeneIds (GRCh38): ENSG00000131910
EnsemblGeneIds (GRCh37): ENSG00000131910
OMIM: 604630, Gene2Phenotype
NR0B2 is in 2 panels

1 review

Krithika Murali (Victorian Clinical Genetics Services)

Red List (low evidence)

Previously also known as SHP1 gene. Polymorphisms associated with obesity.
Created: 27 Mar 2022, 10:35 p.m. | Last Modified: 27 Mar 2022, 10:35 p.m.
Panel Version: 0.12043

Details

Mode of Inheritance
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Sources
  • Expert Review Red
  • Victorian Clinical Genetics Services
Phenotypes
  • Obesity, mild, early-onset, MIM# 601665
OMIM
604630
Clinvar variants
Variants in NR0B2
Penetrance
None
Panels with this gene

History Filter Activity

28 Mar 2022, Gel status: 1

Entity classified by Genomics England curator

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

Gene: nr0b2 has been classified as Red List (Low Evidence).

28 Mar 2022, Gel status: 1

Set mode of inheritance

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

Mode of inheritance for gene: NR0B2 was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted

28 Mar 2022, Gel status: 1

Set Phenotypes

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

Phenotypes for gene: NR0B2 were changed from to Obesity, mild, early-onset, MIM# 601665

28 Mar 2022, Gel status: 1

Entity classified by Genomics England curator

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

Gene: nr0b2 has been classified as Red List (Low Evidence).

17 Nov 2019, Gel status: 3

Created, Added New Source, Set mode of inheritance

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

gene: NR0B2 was added gene: NR0B2 was added to Mendeliome_VCGS. Sources: Expert Review Green,Victorian Clinical Genetics Services Mode of inheritance for gene: NR0B2 was set to Unknown