1. Panels
  2. Interstitial Lung Disease
  3. ZNF341
STRs in panel
Prev Next
Regions in panel
Prev Next

Interstitial Lung Disease

Gene: ZNF341

Red List (low evidence)
ZNF341 (zinc finger protein 341)
EnsemblGeneIds (GRCh38): ENSG00000131061
EnsemblGeneIds (GRCh37): ENSG00000131061
ZNF341 is in 3 panels

1 review

Suzanna Lindsey-Temple (Liverpool Hospital)

Red List (low evidence)

PMID: 29907691 - 3 adults had bronchiectasis or pneumatocele (23, 24, 47yo).

PMID: 29907690 - 2 distinct homozygous nonsense mutations in ZNF341 in 4 autosomal-recessive kindreds with some of the children (1-12 years old) having recurrent and severe pneumonia including necrotising pneumonia but with no reported bronchiectasis.
Created: 6 Nov 2021, 11:26 p.m. | Last Modified: 6 Nov 2021, 11:26 p.m.
Panel Version: 0.183

Mode of inheritance
BIALLELIC, autosomal or pseudoautosomal

Phenotypes
HIES; Bronchiectasis

Publications

Created: 6 Nov 2021, 11:26 p.m.
Last Modified: 6 Nov 2021, 11:26 p.m.
Panel version: 0.183

Details

Mode of Inheritance
BIALLELIC, autosomal or pseudoautosomal
Sources
  • Expert Review Red
Phenotypes
  • Hyper-IgE recurrent infection syndrome 3, autosomal recessive, MIM# 618282
  • Bronchiectasis
Clinvar variants
Variants in ZNF341
Penetrance
None
Publications
Panels with this gene

History Filter Activity

8 Nov 2021, Gel status: 1

Entity classified by Genomics England curator

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

Gene: znf341 has been classified as Red List (Low Evidence).

8 Nov 2021, Gel status: 1

Entity classified by Genomics England curator

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

Gene: znf341 has been classified as Red List (Low Evidence).

8 Nov 2021, Gel status: 0

Set publications

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

Publications for gene: ZNF341 were set to

8 Nov 2021, Gel status: 0

Set Phenotypes

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

Phenotypes for gene: ZNF341 were changed from to Hyper-IgE recurrent infection syndrome 3, autosomal recessive, MIM# 618282; Bronchiectasis

6 Nov 2021, Gel status: 0

Created, Added New Source, Set mode of inheritance

Suzanna Lindsey-Temple (Liverpool Hospital)

gene: ZNF341 was added gene: ZNF341 was added to Interstitial Lung Disease. Sources: Expert list Mode of inheritance for gene: ZNF341 was set to BIALLELIC, autosomal or pseudoautosomal