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  3. RABL3
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Incidentalome

Gene: RABL3

Red List (low evidence)
RABL3 (RAB, member of RAS oncogene family like 3)
EnsemblGeneIds (GRCh38): ENSG00000144840
EnsemblGeneIds (GRCh37): ENSG00000144840
RABL3 is in 1 panel

2 reviews

Bryony Thompson (Royal Melbourne Hospital)

Comment on list classification: One family reported and no replication in other pancreatic cancer cohorts at this point.
Created: 3 Dec 2024, 10:31 p.m. | Last Modified: 3 Dec 2024, 10:31 p.m.
Panel Version: 0.310
Comment on list classification: One family reported and no replication in other pancreatic cancer cohorts at this point.
Created: 3 Dec 2024, 10:30 p.m. | Last Modified: 3 Dec 2024, 10:30 p.m.
Panel Version: 0.309
Created: 3 Dec 2024, 10:30 p.m.
Last Modified: 3 Dec 2024, 10:30 p.m.
Panel version: 0.309

Sue White (Victorian Clinical Genetics Services)

Green List (high evidence)

germline truncating variants associated with increased risk of pancreatic carcinoma
Sources: Literature
Created: 7 Jan 2020, 9:03 a.m.

Mode of inheritance
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted

Phenotypes
pancreatic carcinoma

Publications

Created: 7 Jan 2020, 9:03 a.m.

Panel version: 0.5

Details

Mode of Inheritance
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Sources
  • Expert Review Red
  • Literature
Phenotypes
  • pancreatic carcinoma
Clinvar variants
Variants in RABL3
Penetrance
unknown
Publications
Panels with this gene

History Filter Activity

3 Dec 2024, Gel status: 1

Set publications

Bryony Thompson (Royal Melbourne Hospital)

Publications for gene: RABL3 were set to 31406347

3 Dec 2024, Gel status: 1

Entity classified by Genomics England curator

Bryony Thompson (Royal Melbourne Hospital)

Gene: rabl3 has been classified as Red List (Low Evidence).

3 Dec 2024, Gel status: 1

Entity classified by Genomics England curator

Bryony Thompson (Royal Melbourne Hospital)

Gene: rabl3 has been classified as Red List (Low Evidence).

7 Jan 2020, Gel status: 3

Entity classified by Genomics England curator

Sue White (Victorian Clinical Genetics Services)

Gene: rabl3 has been classified as Green List (High Evidence).

7 Jan 2020, Gel status: 3

Entity classified by Genomics England curator

Sue White (Victorian Clinical Genetics Services)

Gene: rabl3 has been classified as Green List (High Evidence).

7 Jan 2020, Gel status: 1

Created, Added New Source, Set mode of inheritance, Set publications, Set Phenotypes, Set penetrance

Sue White (Victorian Clinical Genetics Services)

gene: RABL3 was added gene: RABL3 was added to Incidentalome_VCGS. Sources: Literature Mode of inheritance for gene: RABL3 was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted Publications for gene: RABL3 were set to 31406347 Phenotypes for gene: RABL3 were set to pancreatic carcinoma Penetrance for gene: RABL3 were set to unknown Review for gene: RABL3 was set to GREEN